1991年10月1日，由亞斯基（ASCII）在Game Boy主機發行的單機遊戲《辟邪除妖》（ウィザードリィ外伝 I 女王の受難/ Wizardry Gaiden I: Suffering of the Queen）。遊戲記憶體容量為2MGB。續作分別於1992年12月26日和1999年2月19日上市。

遊戲劇情與之前系列作品無關，描述用來保護利魯加城的神器格尼爾達之仗力量正逐漸減弱。而艾莉絲女王的妹妹索克斯和邪惡法師泰羅蘇姆失蹤已超過一年。在女王的號召下，勇者們準備打敗邪惡巫師並救回女王的妹妹。

遊戲畫面採用3D立體進行，一開始會出現利魯加城的圖示，透過浮標來決定要去的地方。玩法類似《Wizardry V: Heart of the Maelstrom》，但增加更多的咒語、物品和怪物。

舞台架構包括室內、室外和地下6層，總計有12層樓。可以利用城市作為據點進行補給或獲取訊息。遊戲中可以有6人共同參與競賽，最多可達20人。玩家需要累積經驗值來提升能力。在戰鬥系統中，追加前後衛和武器距離設定指令。遊戲難度遠超過任天堂紅白機三部曲，在咒語的效果上也增加視覺變化。

On October 1, 1991, ASCII released the standalone game "Wizardry Gaiden I: Suffering of the Queen"（ウィザードリィ外伝 I 女王の受難）for the Game Boy portable. The game had a memory capacity of 2MGB. Sequels were released on December 26, 1992, and February 19, 1999, respectively.

The storyline of the game is unrelated to previous series works and revolves around the gradual weakening of the artifact, Staff of Gnilda, used to protect the city of LIygamyn. Alice, the Queen's sister, and the evil sorcerer Tai Rossum/Taros have been missing for over a year. At the Queen's call, the heroes prepare to defeat the evil wizard and rescue the Queen's sister.

The game features 3D graphics, starting with a depiction of Llurg City where players navigate using floating markers to choose destinations. Gameplay is similar to "Wizardry V: Heart of the Maelstrom" but with additional spells, items, and monsters.

The game's setting includes indoor, outdoor, and six underground layers, totaling 12 floors. Players can use the city as a base for resupply or information gathering. Up to six players can compete simultaneously, with a maximum of 20 players. Players must accumulate experience points to enhance their abilities. The battle system includes commands for front and rear guards and weapon distance settings. The game's difficulty surpasses that of the Nintendo Entertainment System trilogy, with visual effects added to spell effects.