日本漫畫之神手塚治虫，出版了許多歷久不衰的漫畫如怪醫黑傑克及火之鳥，而原子小金剛最早在1952~1968年的"少年"漫畫雜誌連載，1953年3月馬上被富士電視改編成真人電視劇，之後更推出電視卡通及電影，直到今日經典作品更是持續推卡通版。

故事描述21世紀的日本科學省省長天馬博士，在一次車禍中痛失獨子，心痛之於將最新技術開發出擁有100萬馬力，可透過腳底火箭發動機飛行的超級機器人。天馬始終無法將小金剛視如己出，於是小金剛輾轉被賣到機器人馬戲團，而在其電腦有不能傷害人類的設定，於是展開與對抗壞人的冒險故事。原子小金剛在FC、SFC及GBA均推出遊戲。

1988年2月26日由柯拿米(Konami)製作發行 在任天堂紅白機(FC)平台首度推出的原子小金剛《原子小金剛/铁臂阿童木》（鉄腕アトム/ Astro Boy / Tetsuwan Atom）遊戲，是以1980年在日本電視播放的動漫為基礎。最早推出的電視版本則是在1963年~1966年在日本富士電視台以黑白動畫呈現。劇情描述地下組織三人幫潛入科學省，並將寶箱偷走。當小金剛趕到並追逐犯人，慢慢發現似乎原來這一切與沉入海底的亞特蘭大有關，於是為了救出擄走的人質神子賽勒那與因多拉，從科學省出發展開救援行動的冒險就此展開。

操作方式很簡單，透過十字鍵就能進行左右移動。A紐是跳躍，B紐是攻擊，按下跟B紐就可以聯繫博士。如果需要起飛就需要跑步後快速三小跳步後就可騰空，只是需要注意下方欄位的TMP欄位，到底的時候就會被迫降落。當在平地走的時候，TMP的箭頭會重新回到最左邊。右下方的顯示是鈾的數量，只要移動或是被敵人擊中都會減少，歸零的時候就失去一台數。

取得金幣是重要的續命關鍵，有足夠的錢才能在打敗後讓博士進行維修續命。總共由十個關卡所組成，第九關救出人質後需要在最後關卡躲過空中攻擊，只要抵達到終點就算全破，可以在開始第二輪的挑戰，難度是大幅提升。

遊戲一開始會從科學省開始，沿路會很多敵人拿火箭筒攻擊，只要被射中馬上掛掉，先讓對方發射砲火後再衝過去攻擊，擊倒後都會拿到金幣，如果在他們後面行走是不會被射擊的。有一些地方只要揮擊就會有金幣掉出來，靠近海的左下方隱藏一些金幣，拿到後再飛越抵達第二個舞台。整體而言這是一款難度不低的遊戲，因為有時間上的限制，加上跳落陷阱或是被敵人擊中就掛掉，又要從頭開始。

雖然每個舞台的路徑都很短，但是沿路的陷阱跟敵人也不少，只要沒有控制跳躍地點或是飛行目的，很容易就陣亡。能玩到最後全破的玩家，應該是出於對動漫的熱愛。在後續舞台需要敲對鈴鐺解開謎底，在冰天雪地的舞台，則須注意移動的方向。值得一提的是FC最後關卡設計跟GBA的原子小金剛～心的秘密有類似之處。

Osamu Tezuka, known as the God of Manga in Japan, published numerous timeless manga series such as "Black Jack" and "Phoenix." "Astro Boy," one of his most famous works, was serialized in the "Shōnen" manga magazine from 1952 to 1968. On March 1953, it was swiftly adapted into a live-action TV series by Fuji Television. Subsequently, it was made into animated TV shows and movies, with classic versions still being produced today.

The story is set in the 21st century and revolves around Dr. Tenma, the head of the Ministry of Science in Japan. After losing his son in a car accident, Dr. Tenma creates a super robot named Astro Boy, equipped with one million horsepower and the ability to fly using rocket boosters in his feet. However, Dr. Tenma could not accept Astro Boy as his real son and eventually sells him to a robot circus. Programmed not to harm humans, Astro Boy embarks on adventures to fight evil. The Astro Boy character has been featured in games for platforms like FC, SFC, and GBA.

On February 26, 1988, Konami released the first Astro Boy game for the Nintendo Famicom (FC). This game, titled "Astro Boy" (鉄腕アトム / Tetsuwan Atom), was based on the 1980s anime series broadcast on Japanese TV. The earliest TV version aired in black and white from 1963 to 1966 on Fuji TV. The plot involves a trio of underground criminals infiltrating the Ministry of Science and stealing a treasure chest. As Astro Boy chases the criminals, he discovers a connection to the sunken Atlantis. Thus begins his rescue mission to save hostages Shinko Serena and Indora, setting off from the Ministry of Science.

The gameplay is straightforward: players move left and right using the D-pad. The A button is for jumping, the B button for attacking, and pressing down and B allows communication with the professor. To fly, players must run and then quickly perform three small jumps. It's crucial to monitor the TMP gauge at the bottom of the screen; when it depletes, Astro Boy will be forced to land. Walking on the ground resets the TMP gauge. The uranium count is displayed in the bottom right corner, which decreases with movement or enemy attacks; reaching zero results in the loss of a life.

Collecting coins is vital for reviving Astro Boy, as sufficient funds allow the professor to repair and extend his life after defeat. The game comprises ten stages, and after rescuing the hostages in stage nine, players must evade aerial attacks in the final stage to reach the endpoint and complete the game, unlocking a more challenging second round.

The game begins at the Ministry of Science, where numerous enemies armed with rocket launchers await. Getting hit means instant death, so players must wait for enemies to fire before attacking. Defeated enemies drop coins. Some areas yield coins when attacked, and hidden coins can be found near the water's edge. Collect them before flying to the second stage. Overall, this game is challenging due to time constraints and the high likelihood of dying from traps or enemy attacks, requiring players to restart from the beginning.

Despite the short stages, the numerous traps and enemies make it difficult to survive without precise jumps and flight. Players who complete the game likely do so out of a love for the anime. In later stages, solving puzzles involves ringing bells, and the icy stages require careful movement. Notably, the final stage design in the FC version shares similarities with the GBA game "Astro Boy: The Secret of the Heart."