1991年12月13日由Natsume製作，Tecmo負責發行的Game Boy單機遊戲《忍者龍劍傳 摩天樓決戰》（忍者龍剣伝GB 摩天楼決戦 / Ninja Gaiden Shadow / Ninja Ryūkenden GB Matenrō Kessen / Legend of the Ninja Dragon Sword GB: Skyscraper Decisive Battle）正式上市，記憶體為2M，無存檔或是密碼續關的設計。許多玩家認為這是Natsume出版的《水上魂斗羅/赤影戰士》（闇の仕事人 KAGE / Shadow of the Ninja / Blue Shadow）修正版本。

故事發生在Jaquio勢力崛起之前。三年前獨裁者嘉魯達皇帝（Garuda）率領軍隊在一個夜黑風高的晚上佔領整個紐約市。在1985年的美國，名為隼龍（Ryu Hayabusa）的男人從黑暗中出現，準備攀爬摩天大樓，企圖阻止邪惡勢力的擴張。沿路會碰到蜘蛛機器人、拳擊冠軍格雷戈里和他的經理傑克。在消滅更多的強敵後，最終任務就是打敗嘉魯達皇帝，讓和平再次的降臨。

A鍵是跳躍，B鍵是揮刀攻擊。按上+A就可以向上射出鎖鏈進行攀爬，按上+B就能使出忍術。整體的動作移動相當流暢，難度大幅降低。總共有五個關卡組成，擊敗關卡的頭目後才能持續移動到下個舞台。流程都不長。主要的武器是武士刀，而之前紅白機版本（Famicom）的攀爬功能則是移除，可以透過鎖鏈進行上下移動。

畫面的左下方為血量欄位，最多有六格，累積的忍術最多有五個，右下方則是生命數。

標題畫面出現時，按 SELECT，輸入以下指令：AAAABBBBABABABAB。如果正確就會聽到蜂鳴聲並進入關卡選單。

標題畫面出現時，按住A鍵，然後同時按B鍵和開始鍵，就可以展開遊戲的所有音樂測試。

在第1、3和5關有隱藏的道具。

在第一關的頭目之前，看到最後一個砲塔，摧毀後按下+A就能地板落下，可以拿到一個忍術。

在第三關的末端，天花板上有機器人會丟擲炸彈，在他的右側地方可以透過鉤子往上爬上去，會拿到生命及忍術。

最後的第五關，在第二階段的舞台，一開始的時候在來的方向走動，按下+A就可以往地板落下，持續下降到底層，進行移動並跳到右邊就可以取得額外的生命數。

On December 13, 1991, the Game Boy standalone game "Ninja Gaiden Shadow" (忍者龍剣伝GB 摩天楼決戦 / Ninja Ryūkenden GB Matenrō Kessen / Legend of the Ninja Dragon Sword GB: Skyscraper Decisive Battle) was released, developed by Natsume and published by Tecmo. It featured 2MB of memory and did not include a save or password feature. Many players considered it a modified version of Natsume's "Shadow of the Ninja" (闇の仕事人 KAGE / Blue Shadow).

The story is set before the rise of Jaquio's forces. Three years ago, the dictator Emperor Garuda led his army to occupy the entire city of New York on a dark and stormy night. In 1985's America, a man named Ryu Hayabusa emerged from the darkness, prepared to climb skyscrapers to stop the spread of evil. Along the way, he encountered spider robots, boxing champion Gregory, and his manager Jack. After defeating more formidable enemies, his ultimate mission was to defeat Emperor Garuda and restore peace.

The A button is for jumping, and the B button is for sword attacks. Pressing Up + A allows Ryu to shoot a grappling hook upwards for climbing, while Up + B performs special ninja techniques. The overall movement and actions are smooth, with significantly less difficulty. There are a total of five stages, and defeating the bosses of each stage allows progression to the next. The main weapon is the katana, and the climbing function from the Famicom version has been removed, replaced by using chains for vertical movement.

The lower left of the screen shows the health meter, with a maximum of six bars, and up to five ninja techniques can be accumulated. The bottom right displays the number of lives.

On the title screen, pressing SELECT and entering the code AAAABBBBABABABAB will trigger a confirmation sound and lead to the level select menu.

While on the title screen, holding the A button and simultaneously pressing the B button and Start will initiate a test of all the game's music tracks.

Hidden items are found in stages 1, 3, and 5.

Before the boss of stage 1, destroying the last turret and pressing Down + A will drop the floor, allowing access to a ninja technique.

At the end of stage 3, robots on the ceiling will throw bombs. Climbing up on the right side using the grappling hook will grant extra life and ninja technique.

In the final stage 5, during the second phase of the stage, moving in the direction of approach and pressing Down + A will descend to the bottom layer. Moving to the right from there allows access to an additional life.