《魯邦三世：潘朵拉的遺產》(ルパン三世 パンドラの遺産/ Lupin Sansei: Pandora no Isan/Lupin the Third: Inheritance of Pandora)是Namco於1987年11月6日在任天堂紅白機(Famicom)主機上推出的遊戲。當時僅在日本上市，並未在其他地區推出。事隔多年有海外玩家的翻譯版本在網路上供人下載。

故事描述以前曾經救過魯邦的克麗絲·德·卡廖斯特羅被人綁架，當收到她的求救信後就起身前往哈魯克的別墅。總共有四個舞台。第一關是哈魯克的別墅，總共有三層，哈魯克就在第一層。第二關是唐人街，要先跟房間內的余先生、梁先生、沙先生跟施先生碰面後就可跟首領吉姆會面。第三關的倉庫分成港口跟倉庫，需要打倒最裡面的頭目拉爾多才能持續前進。第四關則是埃及，搭車前進後就能進入四層樓的立體金字塔，而最底層的中間有克麗絲。

可選擇的人物有魯邦三世、次元大輔或石川五右衛門，魯邦採用近距離射擊，次元的射擊較遠，五右衛門則是揮動武士刀進行近身砍殺。

透過方向鍵來進行移動。A是跳躍，想要高度彈跳按上跟A即可。按B向敵人攻擊。進入通道或房間可以按上。在遊戲進行的時候可以按開始暫停。透過十字鍵的左或是右來選擇想要使用的道具。確認後再解除暫停狀態即可。需注意如果在一個畫面停留太久，錢刑警長就會抓人。被手銬抓住或是碰到就會陣亡，重返選角畫面時臉上就會被戴上手銬，直到通過畫面為止。

當挑戰失敗的時候會回到標題畫面，這時候可以按繼續的指令重新挑戰，但是身上的寶物都會消失。三個人物中只有魯邦才能使用這些寶物。使用後就能持續前進。無線電機是唯一大家能操作的道具。

主要的道具有：

炸彈：能消滅畫面上的所有敵人，但是安置到爆炸為止需要一些時間，這時候要避免敵人的攻擊。

散彈槍：可以連發五枚炸彈，並朝五個方向爆炸，威力與手槍差不多。沒用完的時候碰到敵人就會消失。

飛行噴射器：透過十字鍵來飛行移動，能量快消耗完時會開始閃爍。這時候可以按A紐來著地。

紅外線顯示器：可以在一定時間內發現看不到的陷阱。

水中燈：取得後就能在地下水道穿梭自如，但快失效的時候身邊的泡沫就會增加。

氣球：快掉入陷阱的時候只要按A鈕就能開始漂浮，但碰到天花板時氣球就會爆破。

防彈衣：穿上後可以保護身體免於傷害。

戒指：取得後可以在特定的房間內與巫師跟峰不二子交談後取得重要情報。

如果想要選關的話，可以當標題畫面出現的時候，依序按上下左右BA就能跳到第二關。按左右上下AB就能到第三關。下上右左AA就到第四關。

遊戲的整體難度相當高。三位主角很容易碰到敵人就瞬間死亡。關卡設計採用迷宮的概念，後期敵人的數量相當多，很容易就會掛掉。當迎來最後頭目才發現原來一切都是峰不二子的圈套，利用魯邦來取得神秘的寶藏，而配合演出的克麗絲只是單純想再次見到魯邦。

"Lupin Sansei: Pandora no Isan" (Lupin the Third: Inheritance of Pandora) is a game developed by Namco, released on November 6, 1987, for the Nintendo Famicom console. It was exclusively launched in Japan and did not see a release in other regions. After many years, an overseas player translation version has become available for download on the internet.

The story revolves around the kidnapping of Clarisse, who was previously saved by Lupin III. Upon receiving her distress signal, Lupin III embarks on a journey to Harlock's mansion. The game unfolds across four stages, with the first stage being Harlock's mansion, consisting of three floors, and Harlock located on the first floor. The second stage is Chinatown, where players must meet Mr. Yu, Mr. Leung, Mr. Sha, and Mr. Shi before encountering the boss, Jim. The third stage involves a warehouse divided into a harbor and storage, requiring the defeat of the boss Raldor deep inside to progress. The fourth stage takes place in Egypt, where players enter a four-story pyramid after traveling by car, with Clarisse in the center of the bottom floor.

Players can choose between Lupin III, Jigen, or Goemon, each with their unique abilities—Lupin with close-range shooting, Jigen with long-range shooting, and Goemon using a samurai sword for close combat. Movement is controlled using the directional keys, A is for jumping, and B is for attacking enemies. In tunnels or rooms, players can press up to enter. The game can be paused during play, and items can be selected using the left or right directional keys, confirmed by resuming after pausing.

It's essential to avoid lingering in one screen for too long, as Inspector Zenigata may capture the player. Once caught or touched, the player faces elimination, and upon returning to the character selection screen, handcuffs appear on their face until they progress through the screen.

If a challenge is failed, the game returns to the title screen. Players can use the continue command to retry, but all collected treasures disappear. Only Lupin III among the three characters can use these treasures. The walkie-talkie is the only item that all characters can operate.

Key items include:

Bomb: Eliminates all enemies on the screen, but takes some time to explode, requiring caution against enemy attacks.

Shotgun: Fires five bombs simultaneously in five directions, similar in power to the handgun. Unused bombs disappear upon enemy contact.

Jet Pack: Allows flying and movement using the directional keys, flashing when energy is low. Landing is achieved by pressing the A button.

Infrared Display: Reveals unseen traps within a specific time frame.

Underwater Lamp: Enables easy traversal in underground waterways but produces more foam when close to expiration.

Balloon: Floats when close to falling into a trap, bursting upon ceiling contact.

Bulletproof Vest: Provides protection against damage when worn.

Ring: Grants important information after conversing with wizards and Fujiko Mine in specific rooms.

For those wanting to select levels, on the title screen, sequentially pressing up, down, left, right, B, A jumps to the second stage. Pressing left, right, up, down, A, B jumps to the third stage. Pressing down, up, right, left, A, A jumps to the fourth stage.

The game's overall difficulty is quite high, with the main characters easily facing instant death upon enemy contact. The level design incorporates a maze concept, and later stages feature a considerable number of enemies, making it easy for players to meet their demise. Only in the final stage's encounter with the boss does Lupin III realize that everything was a trap set by Fujiko Mine, exploiting Lupin to obtain the mysterious treasure, while Clarisse's involvement in the performance was merely a desire to see Lupin again.